Transplantation of Reprogrammed Embryonic Stem Cells Improves Visual Function in a Mouse Model for Retinitis Pigmentosa

BACKGROUND: To study whether C57BL/6J-Tyr(c−2j)/J (C2J) mouse embryonic stem (ES) cells can differentiate into retinal pigment epithelial (RPE) cells in vitro and then restore retinal function in a model for retinitis pigmentosa: Rpe65(rd12)/Rpe65(rd12) C57BL6 mice. METHODS: Yellow fluorescent prote...

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Main Authors: Wang, Nan-Kai, Tosi, Joaquin, Kasanuki, Jennifer Mie, Chou, Chai Lin, Kong, Jian, Parmalee, Nancy, Wert, Katherine J., Allikmets, Rando, Lai, Chi-Chun, Chien, Chung-Liang, Nagasaki, Takayuki, Lin, Chyuan-Sheng, Tsang, Stephen H.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855750/
https://ncbi.nlm.nih.gov/pubmed/20164818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181d45a61
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