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Abnormal Post-Translational and Extracellular Processing of Brevican in Plaque-Bearing Mice Overexpressing APPsw

Aggregation of amyloid-β in the forebrain of Alzheimer's disease subjects may disturb the molecular organization of the extracellular microenvironment that modulates neural and synaptic plasticity. Proteoglycans are major components of this extracellular environment. To test the hypothesis that...

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Autori principali: Ajmo, Joanne M., Bailey, Lauren A., Howell, Matthew D., Cortez, Lisa K., Pennypacker, Keith R., Mehta, Hina N., Morgan, Dave, Gordon, Marcia N., Gottschall, Paul E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855738/
https://ncbi.nlm.nih.gov/pubmed/20180882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06647.x
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