Role of CD14 in a Mouse Model of Acute Lung Inflammation Induced by Different Lipopolysaccharide Chemotypes

BACKGROUND: Recognition of lipopolysaccharide (LPS) is required for effective defense against invading gram-negative bacteria. Recently, in vitro studies revealed that CD14 is required for activation of the myeloid differentiation factor (MyD)88-dependent Toll-like receptor (TLR)4 signaling pathway...

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Autors principals: Anas, Adam A., Hovius, Joppe W. R., van 't Veer, Cornelis, van der Poll, Tom, de Vos, Alex F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855719/
https://ncbi.nlm.nih.gov/pubmed/20419140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010183
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