Modular System for the Construction of Zinc-Finger Libraries and Proteins

Engineered zinc-finger transcriptional factors (ZF-TF) are powerful tools to modulate the expression of specific genes. Complex libraries of ZF-TF can be delivered into cells to scan the genome for genes responsible for a particular phenotype or to select the most effective ZF-TF to regulate an indi...

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Main Authors: Gonzalez, Beatriz, Schwimmer, Lauren J., Fuller, Roberta P., Ye, Yongjun, Asawapornmongkol, Lily, Barbas, Carlos F.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855653/
https://ncbi.nlm.nih.gov/pubmed/20360772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2010.34
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