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Development of a Small Peptide Tag for Covalent Labeling of Proteins

A 21-mer peptide that can be used to covalently introduce synthetic molecules into proteins has been developed. Phage displayed peptide libraries were subjected to reaction-based selection with 1,3-diketones. The peptide was further evolved by addition of a randomized region and reselection for impr...

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Detalhes bibliográficos
Main Authors: Tanaka, Fujie, Fuller, Roberta, Asawapornmongkol, Lily, Warsinke, Axel, Gobuty, Sarah, Barbas, Carlos F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518172/
https://ncbi.nlm.nih.gov/pubmed/17602682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc070080x
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