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Development of a Small Peptide Tag for Covalent Labeling of Proteins
A 21-mer peptide that can be used to covalently introduce synthetic molecules into proteins has been developed. Phage displayed peptide libraries were subjected to reaction-based selection with 1,3-diketones. The peptide was further evolved by addition of a randomized region and reselection for impr...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518172/ https://ncbi.nlm.nih.gov/pubmed/17602682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc070080x |
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