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Enzyme Amplified Array Sensing of Proteins in Solution and in Biofluids
We have developed an enzyme-nanoparticle sensor array where the sensitivity is amplified through enzymatic catalysis. In this approach cationic gold nanoparticles are electrostatically bound to an enzyme (β-galactosidase, β-Gal), inhibiting enzyme activity. Analyte proteins release the β-Gal, restor...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855490/ https://ncbi.nlm.nih.gov/pubmed/20329726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1006756 |
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