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Alphavirus replicon-based enhancement of mucosal and systemic immunity is linked to the innate response generated by primary immunization
Venezuelan equine encephalitis virus replicon particles (VRP) function as an effective systemic, cellular and mucosal adjuvant when codelivered with antigen, and show promise for use as a component in new and existing human vaccine formulations. We show here that VRP are effective at low dose and by...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855431/ https://ncbi.nlm.nih.gov/pubmed/20184975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.02.010 |
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