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Clinical Implications of the Intrinsic Efficacy of Beta-Adrenoceptor Drugs in Asthma: Full, Partial and Inverse Agonism

PURPOSE OF THE REVIEW: β(2)-adrenoceptor (AR) agonists are the most effective bronchodilators known, and play important roles in every step of asthma therapy. The intrinsic efficacy is an important pharmacological property that differentiates the clinical effects and safety profile of ß(2)AR agonist...

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Autori principali: Hanania, Nicola A., Dickey, Burton F., Bond, Richard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855430/
https://ncbi.nlm.nih.gov/pubmed/19887938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MCP.0b013e328333def8
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