Assessing the Emergence of Resistance: The Absence of Biological Cost In Vivo May Compromise Fosfomycin Treatments for P. aeruginosa Infections

BACKGROUND: Fosfomycin is a cell wall inhibitor used efficiently to treat uncomplicated urinary tract and gastrointestinal infections. A very convenient feature of fosfomycin, among others, is that although the expected frequency of resistant mutants is high, the biological cost associated with muta...

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Библиографические подробности
Главные авторы: Rodríguez-Rojas, Alexandro, Maciá, María D., Couce, Alejandro, Gómez, Cristina, Castañeda-García, Alfredo, Oliver, Antonio, Blázquez, Jesús
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855370/
https://ncbi.nlm.nih.gov/pubmed/20419114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010193
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