Modulating the Functional Contributions of c-Myc to the Human Endothelial Cell Cyclic Strain Response

This study addresses whether pathological levels of cyclic strain activate the c-Myc promoter, leading to c-Myc transcription and downstream gene induction in human umbilical vein endothelial cells (HUVEC) or human aortic endothelial cells (HAEC). mRNA and protein expression of c-Myc under physiolog...

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Autori principali: Hurley, Nicole E., Schildmeyer, Lisa A., Bosworth, Kami A., Sakurai, Yumiko, Eskin, Suzanne G., Hurley, Laurence H., McIntire, Larry V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2010
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855285/
https://ncbi.nlm.nih.gov/pubmed/19729955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000235928
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