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Transmigration across activated endothelium induces transcriptional changes, inhibits apoptosis, and decreases antimicrobial protein expression in human monocytes

We investigated the hypothesis that transmigration drives monocyte transcriptional changes. Using Agilent whole human genome microarrays, we identified over 692 differentially expressed genes (2×, P<0.05) in freshly isolated human monocytes following 1.5 h of transmigration across IL-1β-stimulate...

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Библиографические подробности
Главные авторы: Williams, Marcie R., Sakurai, Yumiko, Zughaier, Susu M., Eskin, Suzanne G., McIntire, Larry V.
Формат: Artigo
Язык:Inglês
Опубликовано: The Society for Leukocyte Biology 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780914/
https://ncbi.nlm.nih.gov/pubmed/19706840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0209062
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