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Transmigration across activated endothelium induces transcriptional changes, inhibits apoptosis, and decreases antimicrobial protein expression in human monocytes

We investigated the hypothesis that transmigration drives monocyte transcriptional changes. Using Agilent whole human genome microarrays, we identified over 692 differentially expressed genes (2×, P<0.05) in freshly isolated human monocytes following 1.5 h of transmigration across IL-1β-stimulate...

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Hlavní autoři: Williams, Marcie R., Sakurai, Yumiko, Zughaier, Susu M., Eskin, Suzanne G., McIntire, Larry V.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Society for Leukocyte Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780914/
https://ncbi.nlm.nih.gov/pubmed/19706840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0209062
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