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The Role of Hepcidin in Iron Metabolism

Hepcidin is the central regulator of systemic iron homeostasis. Dysregulation of hepcidin production results in a variety of iron disorders. Hepcidin deficiency is the cause of iron overload in hereditary hemochromatosis, iron-loading anemias, and hepatitis C. Hepcidin excess is associated with anem...

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Bibliographic Details
Main Authors: Nemeth, Elizabeta, Ganz, Tomas
Format: Artigo
Language:Inglês
Published: S. Karger AG 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855274/
https://ncbi.nlm.nih.gov/pubmed/19907144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000243791
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