Clinical Responses to Gene Therapy in Joints of Two Subjects with Rheumatoid Arthritis

This paper provides the first evidence of a clinical response to gene therapy in human arthritis. Two subjects with rheumatoid arthritis received ex vivo, intraarticular delivery of human interleukin-1 receptor antagonist (IL-1Ra) cDNA. To achieve this, autologous synovial fibroblasts were transduce...

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Detalhes bibliográficos
Main Authors: Wehling, Peter, Reinecke, Julio, Baltzer, Axel W.A., Granrath, Markus, Schulitz, Klaus P., Schultz, Carl, Krauspe, Rüdiger, Whiteside, Theresa W., Elder, Elaine, Ghivizzani, Steven C., Robbins, Paul D., Evans, Christopher H.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Scientific Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855248/
https://ncbi.nlm.nih.gov/pubmed/18986219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.075
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