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Gene transfer to human joints: Progress toward a gene therapy of arthritis
This article describes the clinical application of gene therapy to a nonlethal disease, rheumatoid arthritis (RA). Intraarticular transfer of IL-1 receptor antagonist (IL-1Ra) cDNA reduces disease in animal models of RA. Whether this procedure is safe and feasible in humans was addressed in a phase...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1150836/ https://ncbi.nlm.nih.gov/pubmed/15939878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502854102 |
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