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Gα13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis

The α subunit of heterotrimeric G13 protein is required for the embryonic angiogenesis (Offermanns et al., Science 275:533–536, 1997). However, the molecular mechanism of Gα13-dependent angiogenesis is not understood. Here, we show that myocyte-specific enhancer factor-2 (MEF2) mediates Gα13-depende...

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Autors principals: Liu, Guoquan, Han, Jingyan, Profirovic, Jasmina, Strekalova, Elena, Voyno-Yasenetskaya, Tatyana A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855211/
https://ncbi.nlm.nih.gov/pubmed/19093215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-008-9123-3
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