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Analysis of FcγRIIA Cytoplasmic Tail Requirements in Signaling for Serotonin Secretion: Evidence for an ITAM-dependent, PI3K-dependent Pathway

The human Fc receptor, FcγRIIA, is known to mediate phagocytosis and endocytosis, yet the greatest numbers of these receptors are expressed on the surface of non-phagocytic platelets, where they are involved in serotonin secretion. FcγRIIA harbors three tyrosine (Y) residues within its cytoplasmic d...

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Detalhes bibliográficos
Main Authors: Daniels, Anthony B., Worth, Randall G., Dickstein, Rian J., Dickstein, Joshua S., Kim-Han, Tae-Hee, Kim, Moo-Kyung, Schreiber, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855141/
https://ncbi.nlm.nih.gov/pubmed/20384866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3083.2010.02369.x
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