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Plasma Cell-free DNA in Ovarian Cancer: An Independent Prognostic Biomarker

BACKGROUND: Cell-free DNA (CFDNA) reflects both normal and tumor-derived DNA released into the circulation through cellular necrosis and apoptosis. We sought to determine the role of pre-operative total plasma CFDNA levels in predicting clinical outcome in patients with ovarian cancer. METHODS: Foll...

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Main Authors: Kamat, Aparna A., Baldwin, Mathew, Urbauer, Diana, Dang, Diana, Han, Liz Y., Godwin, Andrew, Karlan, Beth Y., Simpson, Joe L., Gershenson, David M., Coleman, Robert L., Bischoff, Farideh Z., Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854845/
https://ncbi.nlm.nih.gov/pubmed/20166213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24997
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