Nonerosive arthritis in lupus is mediated by IFN-α stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis

OBJECTIVE: In contrast to rheumatoid arthritis (RA), Jaccoud arthritis (JA) joint inflammation in systemic lupus erythematosus (SLE) is nonerosive. Although the mechanism responsible is unknown, the anti-osteoclastogenic cytokine interferon-alpha (IFN-α), whose transcriptome is present in SLE monocy...

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Autori principali: Mensah, Kofi A., Mathian, Alexis, Ma, Lin, Xing, Lianping, Ritchlin, Christopher T., Schwarz, Edward M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854832/
https://ncbi.nlm.nih.gov/pubmed/20131244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27312
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