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Nonerosive arthritis in lupus is mediated by IFN-α stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis
OBJECTIVE: In contrast to rheumatoid arthritis (RA), Jaccoud arthritis (JA) joint inflammation in systemic lupus erythematosus (SLE) is nonerosive. Although the mechanism responsible is unknown, the anti-osteoclastogenic cytokine interferon-alpha (IFN-α), whose transcriptome is present in SLE monocy...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854832/ https://ncbi.nlm.nih.gov/pubmed/20131244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27312 |
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