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KIR genotype predicts the capacity of human KIR(+) CD56(dim) NK cells to respond to pathogen-associated signals

IFN-γ emanating from natural killer (NK) cells is an important component of innate defence against infection. Here we demonstrate that, following in vitro stimulation of human peripheral blood NK cells with a variety of microbial ligands, CD56(dim) as well as CD56(bright) NK cells contribute to the...

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Detalhes bibliográficos
Main Authors: Korbel, Daniel S., Norman, Paul J., Newman, Kirsty C., Horowitz, Amir, Gendzekhadze, Ketevan, Parham, Peter, Riley, Eleanor M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854670/
https://ncbi.nlm.nih.gov/pubmed/19414796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804224
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