Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca(2+)-Dependent Outward Rectification

Glycine has diverse functions within the mammalian central nervous system. It inhibits postsynaptic neurons via strychnine-sensitive glycine receptors (GlyRs) and enhances neuronal excitation through co-activation of N-methyl-D-aspartate (NMDA) receptors. Classical Ca(2+)-permeable NMDA receptors ar...

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Autors principals: Madry, Christian, Betz, Heinrich, Geiger, Jörg R. P., Laube, Bodo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2010
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854533/
https://ncbi.nlm.nih.gov/pubmed/20407581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2010.00006
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