Critical roles for c-Myb in lymphoid priming and early B-cell development

c-Myb is a transcription factor with functions in many hematopoietic lineages. c-Myb–deficient mice display reduced numbers of B cells; however, it is unknown what role c-Myb plays in B lymphopoiesis because no critical target genes have been identified in the B-cell lineage. We demonstrate that con...

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Bibliografiska uppgifter
Huvudupphovsmän: Greig, Kylie T., de Graaf, Carolyn A., Murphy, James M., Carpinelli, Marina R., Pang, Swee Heng Milon, Frampton, Jon, Kile, Benjamin T., Hilton, Douglas J., Nutt, Stephen L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2010
Ämnen:
Hematopoiesis and Stem Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854426/
https://ncbi.nlm.nih.gov/pubmed/20130238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-239210
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