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Conformational Dynamics and Structural Plasticity Play Critical Roles in Ubiquitin Recognition of a UIM Domain

Ubiquitin-interacting motifs (UIMs) are an important class of protein domains that interact with ubiquitin or ubiquitin-like proteins. These approximately 20 residue-long domains are found in a variety of ubiquitin receptor proteins and serve as recognition modules towards intracellular targets, whi...

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Detalhes bibliográficos
Main Authors: Sgourakis, Nikolaos G., Patel, Mayank M., Garcia, Angel E., Makhatadze, George I., McCallum, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854419/
https://ncbi.nlm.nih.gov/pubmed/20053359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.12.052
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