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Midline Signaling Regulates Kidney Positioning but not Nephrogenesis through Shh

The role of axial structures, especially the notochord, in metanephric kidney development has not been directly examined. Here, we showed that disruption of the notochord and floor plate by diphtheria toxin (DTA)-mediated cell ablation did not disrupt nephrogenesis, but resulted in kidney fusions, r...

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Detalhes bibliográficos
Main Authors: Tripathi, Piyush, Guo, Qiusha, Wang, Yinqiu, Coussens, Matthew, Liapis, Helen, Jain, Sanjay, Kuehn, Michael R., Capecchi, Mario R., Chen, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854326/
https://ncbi.nlm.nih.gov/pubmed/20152829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.02.007
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