Ablation of developing podocytes disrupts cellular interactions and nephrogenesis both inside and outside the glomerulus

Podocyte loss in adults leads to glomerulosclerosis. However, the impact of podocyte loss on glomerulogenesis and the development of the kidney as a whole has not been directly studied. Here, we used a podocyte-specific Cre transgene to direct the production of diphtheria toxin (DTA) inside podocyte...

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Detalhes bibliográficos
Main Authors: Jia, Qunshan, McDill, Bradley W., Sankarapandian, Bala, Wu, Sen, Liapis, Helen, Holzman, Lawrence B., Capecchi, Mario R., Miner, Jeffrey H., Chen, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604822/
https://ncbi.nlm.nih.gov/pubmed/18842818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90519.2008
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