Osteoinductive LIM Mineralization Protein-1 Suppresses Activation of NF-κB and Selectively Regulates MAPK Pathways in Pre-osteoclasts

LIM Mineralization Protein-1 (LMP-1) is an intracellular regulator of bone formation and has been shown to be osteoinductive in vitro and in vivo. The effect of LMP-1 on other aspects of bone homeostasis has not been previously studied. In a pilot study we observed that LMP-1 decreased nitric oxide...

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Main Authors: Liu, Hui, Bargouti, Maggie, Zughaier, Susu, Zheng, Zhaomin, Liu, Yunshan, Sangadala, Sreedhara, Boden, Scott D., Titus, Louisa
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854312/
https://ncbi.nlm.nih.gov/pubmed/19931434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.11.017
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