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Neural crest cell-specific deletion of Rac1 results in defective cell-matrix interactions and severe craniofacial and cardiovascular malformations

The small GTP-binding protein Rac1, a member of the Rho family of small GTPases, has been implicated in regulation of many cellular processes including adhesion, migration and cytokinesis. These functions have largely been attributed to its ability to reorganize cytoskeleton. While the function of R...

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Detalhes bibliográficos
Main Authors: Thomas, Penny S., Kim, Jieun, Nunez, Stephanie, Glogauer, Michael, Kaartinen, Vesa
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854286/
https://ncbi.nlm.nih.gov/pubmed/20184871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.02.021
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