Self-complementary AAV5 Vector Facilitates Quicker Transgene Expression in Photoreceptor and Retinal Pigment Epithelial Cells of Normal Mouse

To clarify whether transduction efficiency and cell type specificity of self-complementary (sc) AAV5 vectors are similar to those of standard, single stranded AAV5 vectors in normal retina, one micro liter of scAAV5-smCBA-GFP vector (1X10(12) genome containing particles/ml) and AAV5-smCBA-GFP vector...

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Detalhes bibliográficos
Main Authors: Kong, Fansheng, Li, Wensheng, Li, Xia, Zheng, Qinxiang, Dai, Xufeng, Zhou, Xiangtian, Boye, Sanford L., Hauswirth, William W., Qu, Jia, Pang, Ji-jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854182/
https://ncbi.nlm.nih.gov/pubmed/20138034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2010.01.011
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