Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway

Understanding the molecular basis and target of traditional medicine is critical for drug development. Celastrol, derived from Trypterygium wilfordii Hook F. (“Thunder of God Vine”), a traditional Chinese medicine plant, has been assigned anticancer activities but its mechanism is not well understoo...

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Hlavní autoři: Pang, Xiufeng, Yi, Zhengfang, Zhang, Jing, Lu, Binbin, Sung, Bokyung, Qu, Weijing, Aggarwal, Bharat B., Liu, Mingyao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854134/
https://ncbi.nlm.nih.gov/pubmed/20160026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3201
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