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The Protein Tyrosine Phosphatase PTP1B Is Required for Efficient Delivery of N-Cadherin to the Cell Surface

PTP1B bound to mature N-cadherin promotes the association of β-catenin into the complex, the stable expression of the complex at cell surface, and cadherin-mediated adhesion. Here we show that PTP1B is also required for N-cadherin precursor trafficking through early stages of the secretory pathway....

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Autori principali: Hernández, Mariana V., Wehrendt, Diana P., Arregui, Carlos O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854096/
https://ncbi.nlm.nih.gov/pubmed/20181825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-10-0880
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