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Protein Kinase Cε inhibits ultraviolet radiation-induced expression of FADD, an adaptor protein, linked to both Fas and TNFR1-mediated apoptosis
PKCε overexpression in FVB/N transgenic mice sensitized skin to ultraviolet radiation (UVR)-induced development of squamous cell carcinomas (SCC) (Wheeler et al., 2004; Wheeler et al., 2005) and suppressed formation of sunburn cells, which are DNA-damaged keratinocytes undergoing apoptosis (Wheeler...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854013/ https://ncbi.nlm.nih.gov/pubmed/19194472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.458 |
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