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Targeted Wild-Type and Jerker Espins Reveal a Novel, WH2 Domain-Dependent Way to Make Actin Bundles in Cells

The espin actin-bundling proteins, which are the target of deafness mutations, are present in the parallel actin bundles of stereocilia and microvilli and appear to increase their steady-state length. Here, we report a new activity of the espins, one that depends on their enigmatic WH2 domain: the a...

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Detalhes bibliográficos
Main Authors: Loomis, Patricia A., Kelly, Alexander E., Zheng, Lili, Changyaleket, Benjarat, Sekerková, Gabriella, Mugnaini, Enrico, Ferreira, Adriana, Mullins, R. Dyche, Bartles, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854011/
https://ncbi.nlm.nih.gov/pubmed/16569662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.02869
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