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The Deaf Jerker Mouse Has a Mutation in the Gene Encoding the Espin Actin-Bundling Proteins of Hair Cell Stereocilia and Fails to Accumulate Espins

The espins are actin-bundling proteins of brush border microvilli and Sertoli cell-spermatid junctions. We have determined that espins are also present in hair cell stereocilia and have uncovered a connection between the espin gene and jerker, a recessive mutation that causes hair cell degeneration,...

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Autori principali: Zheng, Lili, Sekerková, Gabriela, Vranich, Kelly, Tilney, Lewis G., Mugnaini, Enrico, Bartles, James R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850054/
https://ncbi.nlm.nih.gov/pubmed/10975527
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