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Treatment of X-Linked Hypophosphatemia with Calcitriol and Phosphate Increases Circulating Fibroblast Growth Factor 23 Concentrations

Context: X-Linked hypophosphatemia (XLH) is characterized by renal phosphate wasting, with inappropriately low or normal serum 1,25-dihydroxyvitamin D concentrations causing rickets and osteomalacia. Mutations in PHEX result in increased fibroblast growth factor 23 (FGF23) expression, elevating circ...

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Hlavní autoři: Imel, Erik A., DiMeglio, Linda A., Hui, Siu L., Carpenter, Thomas O., Econs, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853995/
https://ncbi.nlm.nih.gov/pubmed/20157195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-1671
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