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Intracellular Redox State Alters NMDA Receptor Response during Aging through Ca(2+)/Calmodulin-Dependent Protein Kinase II
The contribution of the NMDA receptors (NMDARs) to synaptic plasticity declines during aging, and the decline is thought to contribute to memory deficits. Here, we demonstrate that an age-related shift in intracellular redox state contributes to the decline in NMDAR responses through Ca(2+)/calmodul...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853968/ https://ncbi.nlm.nih.gov/pubmed/20130200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5485-09.2010 |
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