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Intracellular Redox State Alters NMDA Receptor Response during Aging through Ca(2+)/Calmodulin-Dependent Protein Kinase II
The contribution of the NMDA receptors (NMDARs) to synaptic plasticity declines during aging, and the decline is thought to contribute to memory deficits. Here, we demonstrate that an age-related shift in intracellular redox state contributes to the decline in NMDAR responses through Ca(2+)/calmodul...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853968/ https://ncbi.nlm.nih.gov/pubmed/20130200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5485-09.2010 |
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