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Drawing the Retinal Out of Its Comfort Zone: An ONIOM(QM/MM) Study of Mutant Squid Rhodopsin

[Image: see text] Engineering squid rhodopsin with modified retinal analogues is essential for understanding the conserved steric and electrostatic interaction networks that govern the architecture of the Schiff base binding site. Depriving the retinal of its steric and electrostatic contacts affect...

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Detalhes bibliográficos
Main Authors: Sekharan, Sivakumar, Morokuma, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853953/
https://ncbi.nlm.nih.gov/pubmed/20396622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz100026k
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