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Drawing the Retinal Out of Its Comfort Zone: An ONIOM(QM/MM) Study of Mutant Squid Rhodopsin

[Image: see text] Engineering squid rhodopsin with modified retinal analogues is essential for understanding the conserved steric and electrostatic interaction networks that govern the architecture of the Schiff base binding site. Depriving the retinal of its steric and electrostatic contacts affect...

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Autores principales: Sekharan, Sivakumar, Morokuma, Keiji
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853953/
https://ncbi.nlm.nih.gov/pubmed/20396622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz100026k
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