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In vivo effects of mesalazine or E. coli Nissle 1917 on microsatellite instability in ulcerative colitis

BACKGROUND: Microsatellite instability (MSI) occurs in chronically inflamed colorectal tissue and may evolve to colitis-associated cancer. In vitro data suggest that mesalazine (5-ASA) improves MSI. AIM: To analyse the changes in MSI in 156 distal colonic biopsies of 39 patients with ulcerative coli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GOEL, A., MITTAL, A., EVSTATIEV, R., NEMETH, M., KRUIS, W., STOLTE, M., BOLAND, C. R., GASCHE, C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853877/
https://ncbi.nlm.nih.gov/pubmed/19558562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2036.2009.04076.x
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