Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states

BACKGROUND: Because of the wide spectrum of clinical manifestations and well-defined immunologic complications, leprosy is a useful disease for studying genetic regulation of the host response to infection. We hypothesized that polymorphisms in NOD2, a cytosolic receptor known to detect mycobacteria...

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Main Authors: Berrington, William Richard, Macdonald, Murdo, Khadge, Saraswoti, Sapkota, Bishwa Raj, Janer, Marta, Hagge, Deanna Alisa, Kaplan, Gilla, Hawn, Thomas Richard
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853728/
https://ncbi.nlm.nih.gov/pubmed/20350193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/651559
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