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Activity and calcium regulate nuclear targeting of the calcium channel β(4b) subunit in nerve and muscle cells

Auxiliary β subunits are critical determinants of membrane expression and gating properties of voltage-gated calcium channels. Mutations in the β(4) subunit gene cause ataxia and epilepsy. However, the specific function of β(4) in neurons and its causal relation to neurological diseases are unknown....

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Autors principals: Subramanyam, Prakash, Obermair, Gerald J., Baumgartner, Sabine, Gebhart, Mathias, Striessnig, Jörg, Kaufmann, Walter A., Geley, Stephan, Flucher, Bernhard E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853709/
https://ncbi.nlm.nih.gov/pubmed/19755859
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