Use of the piggyBac transposon to create HIV-1 gag transgenic insect cell lines for continuous VLP production

BACKGROUND: Insect baculovirus-produced Human immunodeficiency virus type 1 (HIV-1) Gag virus-like-particles (VLPs) stimulate good humoral and cell-mediated immune responses in animals and are thought to be suitable as a vaccine candidate. Drawbacks to this production system include contamination of...

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Bibliographische Detailangaben
Hauptverfasser: Lynch, Alisson G, Tanzer, Fiona, Fraser, Malcolm J, Shephard, Enid G, Williamson, Anna-Lise, Rybicki, Edward P
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853493/
https://ncbi.nlm.nih.gov/pubmed/20356379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-10-30
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