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Effect of apolipoprotein-B synthesis inhibition on liver triglyceride content in patients with familial hypercholesterolemia
To investigate the impact of mipomersen, an apolipoprotein B-100 (apoB) synthesis inhibitor, on intra-hepatic triglyceride content (IHTG content), we conducted a randomized, double-blind, placebo-controlled study in 21 patients with familial hypercholesterolemia (FH). Subjects received a weekly subc...
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Main Authors: | , , , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
The American Society for Biochemistry and Molecular Biology
2010
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853432/ https://ncbi.nlm.nih.gov/pubmed/20008831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M002915 |
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