Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation

Neuroinflammation, caused by 6 days of intracerebroventricular infusion of a low dose of lipopolysaccharide (LPS; 0.5 ng/h), stimulates brain arachidonic acid (AA) metabolism in rats, but 6 weeks of lithium pretreatment reduces this effect. To further understand this action of lithium, we measured c...

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Bibliographische Detailangaben
Hauptverfasser: Basselin, Mireille, Kim, Hyung-Wook, Chen, Mei, Ma, Kaizong, Rapoport, Stanley I., Murphy, Robert C., Farias, Santiago E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853431/
https://ncbi.nlm.nih.gov/pubmed/20040630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M002469
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