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Novel bradykinin signaling in adult rat cardiac myocytes through activation of p21-activated kinase

Although bradykinin (BK) is known to exert effects on the myocardium, its intracellular signaling pathways remain poorly understood. Experiments in other cell types indicated that p21-activated kinase-1 (Pak1), a Ser/Thr kinase downstream of small monomeric G proteins, is activated by BK. We previou...

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Main Authors: Ke, Yunbo, Sheehan, Katherine A., Egom, E. Eroume A., Lei, Ming, Solaro, R. John
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853422/
https://ncbi.nlm.nih.gov/pubmed/20154261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01070.2009
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