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20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H(2)O(2), and PI3-kinase/Akt

We have shown that 20-hydroxyeicosatetraenoic acid (20-HETE) increases both superoxide and nitric oxide (NO) production in bovine pulmonary artery endothelial cells (BPAECs). The current study was designed to determine mechanisms underlying 20-HETE-stimulated NO release, and particularly the role of...

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Bibliografiska uppgifter
Huvudupphovsmän: Bodiga, Sreedhar, Gruenloh, Stephanie K., Gao, Ying, Manthati, Vijay L., Dubasi, Narsimhaswamy, Falck, John R., Medhora, Meetha, Jacobs, Elizabeth R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853341/
https://ncbi.nlm.nih.gov/pubmed/20061439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00298.2009
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