20-HETE increases Superoxide production and activates NADPH Oxidase in Pulmonary Artery Endothelial Cells

Reactive oxygen species (ROS) signal vital physiological processes including cell growth, angiogenesis, contraction, and relaxation of vascular smooth muscle. Because cytochrome P-450 family 4 (CYP4)/20-hydroxyeicosatetraenoic acid (20-HETE) has been reported to enhance angiogenesis, pulmonary vascu...

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Detalhes bibliográficos
Main Authors: Medhora, Meetha, Chen, Yuenmu, Gruenloh, Stephanie, Harland, Daniel, Bodiga, Sreedhar, Zielonka, Jacek, Gebremedhin, Debebe, Gao, Ying, Falck, John R., Anjaiah, Siddam, Jacobs, Elizabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586843/
https://ncbi.nlm.nih.gov/pubmed/18296498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00278.2007
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