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Stress granule formation mediates the inhibition of colonic Hsp70 translation by interferon-γ and tumor necrosis factor-α

Mucosal inflammation, through cytokines such as interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α), has many effects on the intestinal epithelium, including selective translational inhibition of the cytoprotective protein heat shock protein 70 (Hsp70). To further elucidate the mechanisms under...

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Bibliografiske detaljer
Main Authors: Hu, Shien, Claud, Erika C., Musch, Mark W., Chang, Eugene B.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853301/
https://ncbi.nlm.nih.gov/pubmed/20110459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00234.2009
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