The histone variant H2AZ is enriched at Polycomb group target genes in ES cells and is necessary for proper execution of developmental programs

Elucidating how chromatin organization influences gene expression patterns and ultimately cell fate is fundamental to understanding development and disease. Here, we investigate the role of the histone variant H2AZ in embryonic stem (ES) cells because it plays an essential, but poorly understood fun...

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Autori principali: Creyghton, Menno P., Markoulaki, Styliani, Levine, Stuart S., Hanna, Jacob, Lodato, Michael A., Sha, Ky, Young, Richard A., Jaenisch, Rudolf, Boyer, Laurie A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853257/
https://ncbi.nlm.nih.gov/pubmed/18992931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.09.056
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