Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats

TRPA1 agonists cinnamaldehyde (CA) and mustard oil (allyl isothiocyanate= AITC) induce heat hyperalgesia and mechanical allodynia in human skin, and sensitize responses of spinal and trigeminal dorsal horn neurons to noxious skin heating in rats. TRPA1 is also implicated in cold nociception. We pres...

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Autors principals: Tsagareli, Merab G., Tsiklauri, Nana, Zanotto, Karen L., Carstens, Mirela Iodi, Klein, Amanda H., Sawyer, Carolyn M., Gurtskaia, Gulnazi, Abzianidze, Elene, Carstens, E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853256/
https://ncbi.nlm.nih.gov/pubmed/20219630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.02.056
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